Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL

LigandBDBM50582230(CHEMBL5091495)Copy SMILESCopy InChI

Affinity DataIC50:  0.794nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetInterleukin-17A(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL

LigandBDBM50582229(CHEMBL5080633)Copy SMILESCopy InChI

Affinity DataIC50:  1.30nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI