Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Interstitial collagenase
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50183781
((S)-1-((2S,3S)-2-(4-chlorophenyl)-3-(hydroxycarbam...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.700nM
Assay Description:
Binding affinity to recombinant MMP1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50183781
((S)-1-((2S,3S)-2-(4-chlorophenyl)-3-(hydroxycarbam...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2nM
Assay Description:
Binding affinity to recombinant MMP13
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50183781
((S)-1-((2S,3S)-2-(4-chlorophenyl)-3-(hydroxycarbam...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5nM
Assay Description:
Binding affinity to recombinant TACE
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Stromelysin-1
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50183781
((S)-1-((2S,3S)-2-(4-chlorophenyl)-3-(hydroxycarbam...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5nM
Assay Description:
Binding affinity to recombinant MMP3
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50183781
((S)-1-((2S,3S)-2-(4-chlorophenyl)-3-(hydroxycarbam...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 316nM
Assay Description:
Inhibition of LPS/interferon gamma-stimulated TNFalpha release from HPBMC
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI