Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50368786(CHEMBL1791119)Copy SMILESCopy InChI

Affinity DataIC50:  32nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathway
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCathepsin D(Bos taurus)
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50368786(CHEMBL1791119)Copy SMILESCopy InChI

Affinity DataIC50:  120nMAssay Description:Inhibition of conversion of hemoglobin by commercially purchased bovine spleen cathepsin D.More data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI