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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
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kcal/mol
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Found
1
hit in this display
Target
Guanylate cyclase soluble subunit alpha-1
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM463264
(4-Amino-5-(3-fluoro- 4-hydroxyphenyl)-5- methyl-2-...)
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Affinity Data
Ki: 8.55nM
Assay Description:
The binding potencies of sGC compounds to the human recombinant sGC enzyme were determined in a Size Exclusion Chromatography (SEC) competition bindi...
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Ligand Info
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US Patent
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