Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 10 hits in this display
BDBM50250899((4aS,6aS,6bR,8aR,9R,10R,11R,12aR,12bR,14bS)-10,11-...)
BDBM50250899((4aS,6aS,6bR,8aR,9R,10R,11R,12aR,12bR,14bS)-10,11-...)
Ki: 8.30E+3nMAssay Description:Glucose in tail blood was measured using a glucometer (One-Touch Basic; Lifescan, CA). For glucose tolerance tests (GTTs), mice were fasted for 10 ho...More data for this Ligand-Target Pair
BDBM50250899((4aS,6aS,6bR,8aR,9R,10R,11R,12aR,12bR,14bS)-10,11-...)
BDBM50250899((4aS,6aS,6bR,8aR,9R,10R,11R,12aR,12bR,14bS)-10,11-...)
IC50: >4.00E+4nMAssay Description:Inhibition of ovine recombinant COX1 assessed as decrease in formation of PGE2 using arachidonic acid as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
BDBM50250899((4aS,6aS,6bR,8aR,9R,10R,11R,12aR,12bR,14bS)-10,11-...)
BDBM50250899((4aS,6aS,6bR,8aR,9R,10R,11R,12aR,12bR,14bS)-10,11-...)
IC50: >4.00E+4nMAssay Description:Inhibition of human recombinant COX2 expressed in baculovirus infected sf21 cells assessed as decrease in PGE2 formation using arachidonic acid as su...More data for this Ligand-Target Pair
BDBM50250899((4aS,6aS,6bR,8aR,9R,10R,11R,12aR,12bR,14bS)-10,11-...)
BDBM50250899((4aS,6aS,6bR,8aR,9R,10R,11R,12aR,12bR,14bS)-10,11-...)
IC50: 4.20E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in insect cells assessed as decrease in production of 5-HPETE and 5-HETE using arachidonic acid as su...More data for this Ligand-Target Pair
BDBM50250899((4aS,6aS,6bR,8aR,9R,10R,11R,12aR,12bR,14bS)-10,11-...)
BDBM50250899((4aS,6aS,6bR,8aR,9R,10R,11R,12aR,12bR,14bS)-10,11-...)