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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetTissue factor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346613(CHEMBL470029 | Oleanonic Acid)
Affinity DataIC50:  0.221nMAssay Description:Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chosun University

Curated by ChEMBL
LigandPNGBDBM50346613(CHEMBL470029 | Oleanonic Acid)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human recombinant PTP1B after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chosun University

Curated by ChEMBL
LigandPNGBDBM50346613(CHEMBL470029 | Oleanonic Acid)
Affinity DataIC50:  5.32E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chosun University

Curated by ChEMBL
LigandPNGBDBM50346613(CHEMBL470029 | Oleanonic Acid)
Affinity DataIC50:  5.32E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346613(CHEMBL470029 | Oleanonic Acid)
Affinity DataIC50:  1.79E+4nMAssay Description:Inhibition of rabbit muscle GPaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346613(CHEMBL470029 | Oleanonic Acid)
Affinity DataIC50:  1.79E+4nMAssay Description:Inhibition of rabbit muscle glycogen phosphorylase A assessed as release of phosphate from glucose-1-phosphate after 25 mins by microplate reader bas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Dartmouth College

Curated by ChEMBL
LigandPNGBDBM50346613(CHEMBL470029 | Oleanonic Acid)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of inducible nitric oxide synthase in activated macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed