Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL

LigandBDBM50181012((S)-N-hydroxy-2,2-dimethyl-4-(4-(pent-4-ynyloxy)ph...)Copy SMILESCopy InChI

Affinity DataIC50:  8nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL

LigandBDBM50181012((S)-N-hydroxy-2,2-dimethyl-4-(4-(pent-4-ynyloxy)ph...)Copy SMILESCopy InChI

Affinity DataIC50:  11nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL

LigandBDBM50181012((S)-N-hydroxy-2,2-dimethyl-4-(4-(pent-4-ynyloxy)ph...)Copy SMILESCopy InChI

Affinity DataIC50:  40nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI