Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 4 hits in this display
Presenilin-1(Homo sapiens (Human))Centre Hospitalier Universitaire Vaudois (Chuv)
Curated by ChEMBL
IC50: 2.30E+3nMAssay Description:Inhibition of gamma secretase mediated Notch delta E activation in human HeLa cells expressing EGFP after 16 hrs by immunofluorescence analysisMore data for this Ligand-Target Pair
IC50: 2.51E+3nMAssay Description:Inhibition of Notch1 deltaE mutant (unknown origin) expressed in HEK293 cells after 16 hrs by resazurin dye-based luciferase reporter gene assayMore data for this Ligand-Target Pair
IC50: 7.10E+4nMAssay Description:Inhibition of GST-tagged CDK2 (unknown origin) expressed in Escherichia coli in presence of Staurosporine by competitive binding assayMore data for this Ligand-Target Pair