Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetPresenilin-1(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (Chuv)

Curated by ChEMBL
LigandPNGBDBM50110176(CHEMBL3604460)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of gamma secretase mediated Notch delta E activation in human HeLa cells expressing EGFP after 16 hrs by immunofluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50110176(CHEMBL3604460)
Affinity DataIC50:  2.51E+3nMAssay Description:Inhibition of Notch1 deltaE mutant (unknown origin) expressed in HEK293 cells after 16 hrs by resazurin dye-based luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50110176(CHEMBL3604460)
Affinity DataIC50:  7.10E+4nMAssay Description:Non-competitive inhibition of human CDK2/cyclinA using PKTPKKAKKL as substrate in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Hefei University Of Technology

Curated by ChEMBL
LigandPNGBDBM50110176(CHEMBL3604460)
Affinity DataIC50:  7.10E+4nMAssay Description:Inhibition of GST-tagged CDK2 (unknown origin) expressed in Escherichia coli in presence of Staurosporine by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed