Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50154345(CHEMBL3775538)
Affinity DataIC50:  170nMAssay Description:Inhibition of recombinant human GST-tagged CLK1 catalytic domain (129 to 484 residues) expressed in Escherichia coli using GRSRSRSRSRSRSRSR as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50154345(CHEMBL3775538)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged DYRK1A catalytic domain expressed in Escherichia coli BL21(DE3) cells using KKISGRLSPIMTEQ-NH2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50154345(CHEMBL3775538)
Affinity DataIC50:  1.68E+3nMAssay Description:Inhibition of full length recombinant human GST-tagged DYRK1B expressed in insect cells using KKISGRLSPIMTEQ-NH2 as substrate incubated for 15 mins i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50154345(CHEMBL3775538)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 15 mins in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50154345(CHEMBL3775538)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK2 expressed in Escherichia coli BL21(DE3) cells using KKISGRLSPIMTEQ-NH2 as substrate incub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed