Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 21 hits in this display
IC50: 50nMAssay Description:Inhibition of PARP1 in human HeLa cells assessed as reduction in H2O2-induced PAR formation incubated for 30 mins followed by H2O2 addition for 15 mi...More data for this Ligand-Target Pair
IC50: 162nMAssay Description:Inhibition of PARP1 in human HeLa cells assessed as reduction in H2O2-induced PAR formation incubated for 30 mins followed by H2O2 addition for 15 mi...More data for this Ligand-Target Pair
Kd: 1.32E+3nMAssay Description:Displacement of fluorescent probe from human recombinant full length His-tagged PARP1 by fluorescent polarization assayMore data for this Ligand-Target Pair
Kd: 16nMAssay Description:Binding affinity to human recombinant His/GST-tagged PARP1 catalytic domain (655-end residues) by surface plasma resonance methodMore data for this Ligand-Target Pair
Kd: >1.00E+4nMAssay Description:Displacement of fluorescent probe from human recombinant full length His-tagged PARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
Kd: >1.00E+4nMAssay Description:Displacement of fluorescent probe from human recombinant full length His-tagged PARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
Kd: >1.00E+4nMAssay Description:Displacement of fluorescent probe from human recombinant His-tagged TNKS1 catalytic domain (1091-1325 residues) by fluorescent polarization assayMore data for this Ligand-Target Pair
Kd: >1.00E+4nMAssay Description:Displacement of fluorescent probe from human recombinant His-tagged TNKS1 catalytic domain (1091-1325 residues) by fluorescent polarization assayMore data for this Ligand-Target Pair
Kd: 1.76E+3nMAssay Description:Binding affinity to human recombinant His/GST-tagged PARP1 catalytic domain (655-end residues) by surface plasma resonance methodMore data for this Ligand-Target Pair
Kd: 10nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
Kd: 10nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair