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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
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Target
Neuromedin-K receptor
(Homo sapiens (Human))
Ogeda
US Patent
Ligand
BDBM430695
((4-fluorophenyl)(8-methyl-3-(quinolin-2-yl)-5,6-di...)
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Affinity Data
Ki: <500nM
Assay Description:
The ability of the compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist SB222200 was assessed by an in vitro r...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Neuromedin-K receptor
(Homo sapiens (Human))
Ogeda
US Patent
Ligand
BDBM430732
((R)-(4-fluorophenyl)(8-methyl-3-(quinolin-2-yl)-5,...)
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Affinity Data
Ki: <500nM
Assay Description:
The ability of the compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist SB222200 was assessed by an in vitro r...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Neuromedin-K receptor
(Homo sapiens (Human))
Ogeda
US Patent
Ligand
BDBM430743
((S)-(4-fluorophenyl)(8-methyl-3-(quinolin-2-yl)-5,...)
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Affinity Data
Ki: <500nM
Assay Description:
The ability of the compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist SB222200 was assessed by an in vitro r...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Neuromedin-K receptor
(Homo sapiens (Human))
Ogeda
US Patent
Ligand
BDBM430732
((R)-(4-fluorophenyl)(8-methyl-3-(quinolin-2-yl)-5,...)
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Copy InChI
Affinity Data
IC50: 260nM
Assay Description:
Antagonistic activity against NK3R (unknown origin) expressed in CHO cells assessed as inhibition of NKB-induced intracellular calcium flux by Calciu...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI