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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Endothelin-converting enzyme 1
(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50046821
(4-[2-(2-tert-Butoxycarbonylamino-3-methyl-pentanoy...)
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Affinity Data
IC50: 370nM
Assay Description:
Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cathepsin D
(Bos taurus)
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50046821
(4-[2-(2-tert-Butoxycarbonylamino-3-methyl-pentanoy...)
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Affinity Data
IC50: 2.60E+3nM
Assay Description:
Inhibition of conversion of hemoglobin by commercially purchased bovine spleen cathepsin D.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Renin
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50046821
(4-[2-(2-tert-Butoxycarbonylamino-3-methyl-pentanoy...)
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Affinity Data
IC50: >1.00E+4nM
pH: 6.0
Assay Description:
In vitro inhibition of partially purified human renin at pH 6.0.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI