Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 6 hits in this display
BDBM301449(7-{1-[1-(2-fluorophenyl)-1H-1,2,3-triazol-4-yl]pro...)
BDBM301449(7-{1-[1-(2-fluorophenyl)-1H-1,2,3-triazol-4-yl]pro...)
BDBM301449(7-{1-[1-(2-fluorophenyl)-1H-1,2,3-triazol-4-yl]pro...)
EC50: 5.83nMAssay Description:Fischer rat thyroid (FRT) cell lines stably expressing recombinant F508del V470 CFTR and halide-sensitive yellow fluorescent protein (Pedemonte et al...More data for this Ligand-Target Pair
BDBM301449(7-{1-[1-(2-fluorophenyl)-1H-1,2,3-triazol-4-yl]pro...)
EC50: 91.2nMAssay Description:Fischer rat thyroid (FRT) cell lines stably expressing recombinant F508del V470 CFTR and halide-sensitive yellow fluorescent protein (Pedemonte et al...More data for this Ligand-Target Pair
BDBM301449(7-{1-[1-(2-fluorophenyl)-1H-1,2,3-triazol-4-yl]pro...)
EC50: 4.93nMAssay Description:Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...More data for this Ligand-Target Pair
BDBM301449(7-{1-[1-(2-fluorophenyl)-1H-1,2,3-triazol-4-yl]pro...)
EC50: 36.6nMAssay Description:Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...More data for this Ligand-Target Pair