Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetNeprilysin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50190739((R)-2-((1-((5-methyl-1,3,4-thiadiazol-2-yl)carbamo...)Copy SMILESCopy InChI

Affinity DataIC50:  114nMAssay Description:Inhibition of dog NEPMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50190739((R)-2-((1-((5-methyl-1,3,4-thiadiazol-2-yl)carbamo...)Copy SMILESCopy InChI

Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of dog ACEMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50190739((R)-2-((1-((5-methyl-1,3,4-thiadiazol-2-yl)carbamo...)Copy SMILESCopy InChI

Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of human ECE1More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI