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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
17
hits in this display
Target
Reverse transcriptase
(Human immunodeficiency virus 1)
2-Universit£
Curated by
ChEMBL
Ligand
BDBM50339536
((+/-)-6-Ethyl-6-[4-[(2-chloro-4-fluorophenylthio)m...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 10nM
Assay Description:
Inhibition of HIV1 wild type reverse transcriptase/poly(rA)/oligo(dT) DNA/dTTP ternary complex
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Reverse transcriptase protein
(Human immunodeficiency virus 1)
2-Universit£
Curated by
ChEMBL
Ligand
BDBM50339536
((+/-)-6-Ethyl-6-[4-[(2-chloro-4-fluorophenylthio)m...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 20nM
Assay Description:
Inhibition of HIV1 reverse transcriptase K103N mutant/poly(rA)/oligo(dT) DNA/dTTP ternary complex
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Reverse transcriptase
(Human immunodeficiency virus 1)
2-Universit£
Curated by
ChEMBL
Ligand
BDBM50339536
((+/-)-6-Ethyl-6-[4-[(2-chloro-4-fluorophenylthio)m...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 90nM
Assay Description:
Inhibition of HIV1 wild type reverse transcriptase/poly(rA)/oligo(dT) DNA binary complex
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Reverse transcriptase
(Human immunodeficiency virus 1)
2-Universit£
Curated by
ChEMBL
Ligand
BDBM50339536
((+/-)-6-Ethyl-6-[4-[(2-chloro-4-fluorophenylthio)m...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 90nM
Assay Description:
Inhibition of HIV1 free wild type reverse transcriptase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Reverse transcriptase
(Human immunodeficiency virus 1)
2-Universit£
Curated by
ChEMBL
Ligand
BDBM50339536
((+/-)-6-Ethyl-6-[4-[(2-chloro-4-fluorophenylthio)m...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 120nM
Assay Description:
Inhibition of HIV1 reverse transcriptase V179D mutant/poly(rA)/oligo(dT) DNA/dTTP ternary complex
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Reverse transcriptase
(Human immunodeficiency virus 1)
2-Universit£
Curated by
ChEMBL
Ligand
BDBM50339536
((+/-)-6-Ethyl-6-[4-[(2-chloro-4-fluorophenylthio)m...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 140nM
Assay Description:
Inhibition of HIV1 reverse transcriptase V179D mutant/poly(rA)/oligo(dT) DNA binary complex
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Reverse transcriptase
(Human immunodeficiency virus 1)
2-Universit£
Curated by
ChEMBL
Ligand
BDBM50339536
((+/-)-6-Ethyl-6-[4-[(2-chloro-4-fluorophenylthio)m...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 140nM
Assay Description:
Inhibition of HIV1 free reverse transcriptase V179D mutant
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Reverse transcriptase protein
(Human immunodeficiency virus 1)
2-Universit£
Curated by
ChEMBL
Ligand
BDBM50339536
((+/-)-6-Ethyl-6-[4-[(2-chloro-4-fluorophenylthio)m...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 150nM
Assay Description:
Inhibition of HIV1 reverse transcriptase L100I mutant/poly(rA)/oligo(dT) DNA/dTTP ternary complex
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Reverse transcriptase protein
(Human immunodeficiency virus 1)
2-Universit£
Curated by
ChEMBL
Ligand
BDBM50339536
((+/-)-6-Ethyl-6-[4-[(2-chloro-4-fluorophenylthio)m...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 200nM
Assay Description:
Inhibition of HIV1 free reverse transcriptase L100I mutant
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Reverse transcriptase protein
(Human immunodeficiency virus 1)
2-Universit£
Curated by
ChEMBL
Ligand
BDBM50339536
((+/-)-6-Ethyl-6-[4-[(2-chloro-4-fluorophenylthio)m...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 200nM
Assay Description:
Inhibition of HIV1 reverse transcriptase L100I mutant/poly(rA)/oligo(dT) DNA binary complex
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Reverse transcriptase protein
(Human immunodeficiency virus 1)
2-Universit£
Curated by
ChEMBL
Ligand
BDBM50339536
((+/-)-6-Ethyl-6-[4-[(2-chloro-4-fluorophenylthio)m...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 510nM
Assay Description:
Inhibition of HIV1 reverse transcriptase K103N mutant/poly(rA)/oligo(dT) DNA binary complex
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Reverse transcriptase protein
(Human immunodeficiency virus 1)
2-Universit£
Curated by
ChEMBL
Ligand
BDBM50339536
((+/-)-6-Ethyl-6-[4-[(2-chloro-4-fluorophenylthio)m...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 510nM
Assay Description:
Inhibition of HIV1 free reverse transcriptase K103N mutant
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Reverse transcriptase
(Human immunodeficiency virus 1)
2-Universit£
Curated by
ChEMBL
Ligand
BDBM50339536
((+/-)-6-Ethyl-6-[4-[(2-chloro-4-fluorophenylthio)m...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 610nM
Assay Description:
Inhibition of HIV1 wild type reverse transcriptase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Adenosine kinase
(Homo sapiens (Human))
Universita` Di Siena
Curated by
ChEMBL
Ligand
BDBM50339536
((+/-)-6-Ethyl-6-[4-[(2-chloro-4-fluorophenylthio)m...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.50E+3nM
Assay Description:
Inhibition of human adenosine kinase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Reverse transcriptase protein
(Human immunodeficiency virus 1)
2-Universit£
Curated by
ChEMBL
Ligand
BDBM50339536
((+/-)-6-Ethyl-6-[4-[(2-chloro-4-fluorophenylthio)m...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.05E+4nM
Assay Description:
Inhibition of HIV1 reverse transcriptase K103N mutant
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Reverse transcriptase
(Human immunodeficiency virus 1)
2-Universit£
Curated by
ChEMBL
Ligand
BDBM50339536
((+/-)-6-Ethyl-6-[4-[(2-chloro-4-fluorophenylthio)m...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >4.00E+4nM
Assay Description:
Inhibition of HIV1 reverse transcriptase V179D mutant
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Reverse transcriptase protein
(Human immunodeficiency virus 1)
2-Universit£
Curated by
ChEMBL
Ligand
BDBM50339536
((+/-)-6-Ethyl-6-[4-[(2-chloro-4-fluorophenylthio)m...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >4.00E+5nM
Assay Description:
Inhibition of HIV1 reverse transcriptase L100I mutant
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI