Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
The University Of Manchester

Curated by ChEMBL

LigandBDBM50184760((2S,3S,4S)-methyl 1-benzyl-2-ethyl-4-hydroxy-5-(2-...)Copy SMILESCopy InChI

Affinity DataIC50:  1.97E+4nMAssay Description:Inhibition of DNA polymerase alphaMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetDNA polymerase beta(Homo sapiens (Human))
The University Of Manchester

Curated by ChEMBL

LigandBDBM50184760((2S,3S,4S)-methyl 1-benzyl-2-ethyl-4-hydroxy-5-(2-...)Copy SMILESCopy InChI

Affinity DataIC50:  2.71E+4nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetDNA nucleotidylexotransferase(Homo sapiens (Human))
The University Of Manchester

Curated by ChEMBL

LigandBDBM50184760((2S,3S,4S)-methyl 1-benzyl-2-ethyl-4-hydroxy-5-(2-...)Copy SMILESCopy InChI

Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human TdTMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI