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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Hypoxia-inducible factor 1-alpha inhibitor
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50580321
(CHEMBL5091848)
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Affinity Data
IC50: 4.00E+3nM
Assay Description:
Inhibition of human FIH using HLEVVKLLLEAGADVNAQDK-CONH2 as substrate preincubated for 15 mins followed by substrate addition and measured after 15 m...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Lysine-specific demethylase 4A
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50580321
(CHEMBL5091848)
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Affinity Data
IC50: 1.34E+4nM
Assay Description:
Inhibition of human N-terminal His6-tagged KDM4A (M1 to L359 residues) expressed in Escherichia coli using H3K9(Me3) as substrate preincubated for 15...
More data for this Ligand-Target Pair
Target Info
PDB
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antibodypedia
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Ligand Info
PC cid
PC sid
In Depth
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Article
PubMed
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Target
Lysine-specific demethylase 4D
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50580321
(CHEMBL5091848)
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Affinity Data
IC50: 1.98E+4nM
Assay Description:
Inhibition of human N-terminal His6-tagged KDM4D (M1 to G373 residues) expressed in Escherichia coli using H3K9(Me3) as substrate preincubated for 15...
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Target Info
PDB
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PC sid
In Depth
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Article
PubMed
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Target
Lysine-specific demethylase 5B
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50580321
(CHEMBL5091848)
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Affinity Data
IC50: 2.26E+4nM
Assay Description:
Inhibition of human N-terminal His6-tagged KDM5B (L882 to S1761 residues) expressed in insect cells using H3K4(Me3) as substrate preincubated for 15 ...
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Article
PubMed
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Target
Lysine-specific demethylase 2A
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50580321
(CHEMBL5091848)
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Affinity Data
IC50: 5.84E+4nM
Assay Description:
Inhibition of human N-terminal His6-tagged KDM2A (M1 to P517 residues) expressed in insect cells using H3K36(Me2) as substrate preincubated for 15 mi...
More data for this Ligand-Target Pair
Target Info
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antibodypedia
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PC sid
In Depth
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Article
PubMed
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Target
Lysine-specific demethylase 3B
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50580321
(CHEMBL5091848)
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Affinity Data
IC50: 6.68E+4nM
Assay Description:
Inhibition of human N-terminal His6-tagged KDM3B (L882 to S1761 residues) expressed in insect cells using H3K9(Me2) as substrate preincubated for 15 ...
More data for this Ligand-Target Pair
Target Info
PDB
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PC sid
In Depth
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Article
PubMed
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Target
Lysine-specific demethylase 6B
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50580321
(CHEMBL5091848)
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Affinity Data
IC50: 6.71E+4nM
Assay Description:
Inhibition of human KDM6B (D1141 to R1641 residues) expressed in Escherichia coli using H3K27(Me3) as substrate preincubated for 15 mins followed by ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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