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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Endothelin-1 receptor
(RAT)
Shionogi
Curated by
ChEMBL
Ligand
BDBM50112679
(2-Benzo[1,3]dioxol-5-yl-4-pentyloxy-2H-chromene-3-...)
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Affinity Data
IC50: 29nM
Assay Description:
Binding affinity for endothelin A receptor by inhibition of [125I]-ET-1 binding in rat aorta smooth muscle cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Endothelin-1 receptor
(RAT)
Shionogi
Curated by
ChEMBL
Ligand
BDBM50112679
(2-Benzo[1,3]dioxol-5-yl-4-pentyloxy-2H-chromene-3-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 29nM
Assay Description:
Ability to displace [125I]-ET-1 from the rat endothelin A receptor expressed in rat aorta smooth muscle cells.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Endothelin receptor type B
(Sus scrofa)
Shionogi
Curated by
ChEMBL
Ligand
BDBM50112679
(2-Benzo[1,3]dioxol-5-yl-4-pentyloxy-2H-chromene-3-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.10E+3nM
Assay Description:
Binding affinity to endothelin B receptor measured by inhibition of [125I]-ET-3 binding recombinant pig ET-B receptor expressed in COS-7 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI