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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM50444249(CHEMBL3093748 | US9649309, Compound UNC2776A)
Affinity DataIC50:  11nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Eshelman School Of Pharmacy�Department Of Pharmacology�Lineberger Compreh

Curated by ChEMBL
LigandPNGBDBM50444249(CHEMBL3093748 | US9649309, Compound UNC2776A)
Affinity DataIC50:  15nMAssay Description:Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Eshelman School Of Pharmacy�Department Of Pharmacology�Lineberger Compreh

Curated by ChEMBL
LigandPNGBDBM50444249(CHEMBL3093748 | US9649309, Compound UNC2776A)
Affinity DataIC50:  15nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Eshelman School Of Pharmacy�Department Of Pharmacology�Lineberger Compreh

Curated by ChEMBL
LigandPNGBDBM50444249(CHEMBL3093748 | US9649309, Compound UNC2776A)
Affinity DataIC50:  55nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGrowth arrest-specific protein 6(Homo sapiens (Human))
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM50444249(CHEMBL3093748 | US9649309, Compound UNC2776A)
Affinity DataIC50:  658nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
Eshelman School Of Pharmacy�Department Of Pharmacology�Lineberger Compreh

Curated by ChEMBL
LigandPNGBDBM50444249(CHEMBL3093748 | US9649309, Compound UNC2776A)
Affinity DataIC50:  660nMAssay Description:Inhibition of Tyro-3 kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
Eshelman School Of Pharmacy�Department Of Pharmacology�Lineberger Compreh

Curated by ChEMBL
LigandPNGBDBM50444249(CHEMBL3093748 | US9649309, Compound UNC2776A)
Affinity DataIC50:  880nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Eshelman School Of Pharmacy�Department Of Pharmacology�Lineberger Compreh

Curated by ChEMBL
LigandPNGBDBM50444249(CHEMBL3093748 | US9649309, Compound UNC2776A)
Affinity DataIC50:  880nMAssay Description:Inhibition of Axl kinase (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed