Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50175535
(2-(4-Butoxy-benzenesulfonylamino)-N-hydroxy-acetam...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.40nM
Assay Description:
Inhibition of human recombinant MMP2 using Mca-Lys-Pro- Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 2 hrs prior to substrate addition...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50175535
(2-(4-Butoxy-benzenesulfonylamino)-N-hydroxy-acetam...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7nM
Assay Description:
Inhibition of human recombinant MMP13 using Mca-Lys-Pro- Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 2 hrs prior to substrate additio...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-14
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50175535
(2-(4-Butoxy-benzenesulfonylamino)-N-hydroxy-acetam...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 71nM
Assay Description:
Inhibition of human recombinant MMP14 catalytic domain using Mca-Lys-Pro- Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 2 hrs prior to ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
De Novo Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50175535
(2-(4-Butoxy-benzenesulfonylamino)-N-hydroxy-acetam...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 920nM
Assay Description:
Inhibitory concentration against (MMP-1) matrix metalloproteinase-1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
A disintegrin and metalloproteinase with thrombospondin motifs 4
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50175535
(2-(4-Butoxy-benzenesulfonylamino)-N-hydroxy-acetam...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.30E+3nM
Assay Description:
Inhibition of human recombinant ADAMTS4 expressed in HEk293 cells using FAM-AEwLQGRPISIAK-TAMRA as substrate measured for 15 mins by fluorometric ana...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50175535
(2-(4-Butoxy-benzenesulfonylamino)-N-hydroxy-acetam...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.40E+3nM
Assay Description:
Inhibition of human recombinant ADAMTS5 expressed in HEK293 cells using Abz-TESEwSRGAIY-Dpa-KK as substrate measured for 2 hrs by fluorometric analys...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
De Novo Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50175535
(2-(4-Butoxy-benzenesulfonylamino)-N-hydroxy-acetam...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.10E+4nM
Assay Description:
Inhibition of human recombinant MMP1 using Mca-Lys-Pro- Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 2 hrs prior to substrate addition...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI