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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50311412
(CHEMBL1080046 | N-(3-((1H-pyrazol-3-yl)methyl)-2,3...)
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Affinity Data
IC50: 600nM
Assay Description:
Inhibition of human recombinant CYP2C9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50311412
(CHEMBL1080046 | N-(3-((1H-pyrazol-3-yl)methyl)-2,3...)
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Affinity Data
IC50: 800nM
Assay Description:
Inhibition of human recombinant CYP3A4 using diethoxyfluorescein as substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50311412
(CHEMBL1080046 | N-(3-((1H-pyrazol-3-yl)methyl)-2,3...)
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Affinity Data
IC50: 1.90E+3nM
Assay Description:
Inhibition of human recombinant CYP3A4 using 7-{3-(4-phenylpiperazin-1-ylmethyl)benzyl}resorufin as substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50311412
(CHEMBL1080046 | N-(3-((1H-pyrazol-3-yl)methyl)-2,3...)
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Affinity Data
IC50: 2.51E+3nM
Assay Description:
Inhibition of human ERG
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cytochrome P450 2C19
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50311412
(CHEMBL1080046 | N-(3-((1H-pyrazol-3-yl)methyl)-2,3...)
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Affinity Data
IC50: 8.80E+3nM
Assay Description:
Inhibition of human recombinant CYP2C19
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cytochrome P450 1A2
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50311412
(CHEMBL1080046 | N-(3-((1H-pyrazol-3-yl)methyl)-2,3...)
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Affinity Data
IC50: 2.90E+4nM
Assay Description:
Inhibition of human recombinant CYP1A2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50311412
(CHEMBL1080046 | N-(3-((1H-pyrazol-3-yl)methyl)-2,3...)
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Affinity Data
EC50: 79.4nM
Assay Description:
Agonist activity at human gherlin receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Motilin receptor
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50311412
(CHEMBL1080046 | N-(3-((1H-pyrazol-3-yl)methyl)-2,3...)
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Affinity Data
EC50: 2.51nM
Assay Description:
Agonist activity at human recombinant motilin receptor expressed in CHO cells by FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI