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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 19 hits in this display   

TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50:  171nMAssay Description:Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50:  340nMAssay Description:Inhibition of recombinant LMWPTP (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 13(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50:  390nMAssay Description:Inhibition of recombinant FAP-1 (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50:  470nMAssay Description:Inhibition of recombinant PTPbeta (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50:  560nMAssay Description:Inhibition of recombinant SHP-2 (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50:  590nMAssay Description:Inhibition of recombinant PTP-MEG2 (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 12(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50:  800nMAssay Description:Inhibition of recombinant PTP-PEST (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50:  910nMAssay Description:Inhibition of recombinant SHP-1 (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 3(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of recombinant PTPH1 (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 15(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of recombinant VHX (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of recombinant HEPTP (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of recombinant CD45 (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 23(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of recombinant VHZ (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase gamma(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of recombinant PTPgamma (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of recombinant VHR (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of recombinant PTPmu (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of recombinant TCPTP (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase epsilon(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of recombinant PTPepsilon (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed