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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
19
hits in this display
Target
Tyrosine-protein phosphatase non-receptor type 22
(Homo sapiens (Human))
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50436358
(CHEMBL2396718)
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Affinity Data
IC50: 171nM
Assay Description:
Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...
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Target
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human))
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50436358
(CHEMBL2396718)
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Affinity Data
IC50: 340nM
Assay Description:
Inhibition of recombinant LMWPTP (unknown origin) using pNPP as substrate by spectrophotometric analysis
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Target
Tyrosine-protein phosphatase non-receptor type 13
(Homo sapiens (Human))
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50436358
(CHEMBL2396718)
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Affinity Data
IC50: 390nM
Assay Description:
Inhibition of recombinant FAP-1 (unknown origin) using pNPP as substrate by spectrophotometric analysis
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Target
Receptor-type tyrosine-protein phosphatase beta
(Homo sapiens (Human))
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50436358
(CHEMBL2396718)
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Affinity Data
IC50: 470nM
Assay Description:
Inhibition of recombinant PTPbeta (unknown origin) using pNPP as substrate by spectrophotometric analysis
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Target
Tyrosine-protein phosphatase non-receptor type 11
(Homo sapiens (Human))
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50436358
(CHEMBL2396718)
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Affinity Data
IC50: 560nM
Assay Description:
Inhibition of recombinant SHP-2 (unknown origin) using pNPP as substrate by spectrophotometric analysis
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Target Info
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Target
Tyrosine-protein phosphatase non-receptor type 9
(Homo sapiens (Human))
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50436358
(CHEMBL2396718)
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Affinity Data
IC50: 590nM
Assay Description:
Inhibition of recombinant PTP-MEG2 (unknown origin) using pNPP as substrate by spectrophotometric analysis
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Target
Tyrosine-protein phosphatase non-receptor type 12
(Homo sapiens (Human))
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50436358
(CHEMBL2396718)
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Affinity Data
IC50: 800nM
Assay Description:
Inhibition of recombinant PTP-PEST (unknown origin) using pNPP as substrate by spectrophotometric analysis
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Target
Tyrosine-protein phosphatase non-receptor type 6
(Homo sapiens (Human))
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50436358
(CHEMBL2396718)
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Affinity Data
IC50: 910nM
Assay Description:
Inhibition of recombinant SHP-1 (unknown origin) using pNPP as substrate by spectrophotometric analysis
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Target Info
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Target
Tyrosine-protein phosphatase non-receptor type 3
(Homo sapiens (Human))
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50436358
(CHEMBL2396718)
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Affinity Data
IC50: 1.60E+3nM
Assay Description:
Inhibition of recombinant PTPH1 (unknown origin) using pNPP as substrate by spectrophotometric analysis
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Target
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human))
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50436358
(CHEMBL2396718)
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Affinity Data
IC50: 1.70E+3nM
Assay Description:
Inhibition of recombinant PTP1B (unknown origin) using pNPP as substrate by spectrophotometric analysis
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Target
Dual specificity protein phosphatase 15
(Homo sapiens (Human))
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50436358
(CHEMBL2396718)
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Affinity Data
IC50: 2.90E+3nM
Assay Description:
Inhibition of recombinant VHX (unknown origin) using pNPP as substrate by spectrophotometric analysis
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Target
Tyrosine-protein phosphatase non-receptor type 7
(Homo sapiens (Human))
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50436358
(CHEMBL2396718)
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Affinity Data
IC50: 3.00E+3nM
Assay Description:
Inhibition of recombinant HEPTP (unknown origin) using pNPP as substrate by spectrophotometric analysis
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Target
Receptor-type tyrosine-protein phosphatase C
(Homo sapiens (Human))
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50436358
(CHEMBL2396718)
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Affinity Data
IC50: 3.20E+3nM
Assay Description:
Inhibition of recombinant CD45 (unknown origin) using pNPP as substrate by spectrophotometric analysis
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Target
Dual specificity protein phosphatase 23
(Homo sapiens (Human))
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50436358
(CHEMBL2396718)
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Affinity Data
IC50: 3.40E+3nM
Assay Description:
Inhibition of recombinant VHZ (unknown origin) using pNPP as substrate by spectrophotometric analysis
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Target
Receptor-type tyrosine-protein phosphatase gamma
(Homo sapiens (Human))
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50436358
(CHEMBL2396718)
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Affinity Data
IC50: 4.00E+3nM
Assay Description:
Inhibition of recombinant PTPgamma (unknown origin) using pNPP as substrate by spectrophotometric analysis
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Target
Dual specificity protein phosphatase 3
(Homo sapiens (Human))
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50436358
(CHEMBL2396718)
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Affinity Data
IC50: 5.90E+3nM
Assay Description:
Inhibition of recombinant VHR (unknown origin) using pNPP as substrate by spectrophotometric analysis
More data for this Ligand-Target Pair
Target Info
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Target
Receptor-type tyrosine-protein phosphatase mu
(Homo sapiens (Human))
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50436358
(CHEMBL2396718)
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Affinity Data
IC50: 7.00E+3nM
Assay Description:
Inhibition of recombinant PTPmu (unknown origin) using pNPP as substrate by spectrophotometric analysis
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Target Info
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Target
Tyrosine-protein phosphatase non-receptor type 2
(Homo sapiens (Human))
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50436358
(CHEMBL2396718)
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Affinity Data
IC50: 1.13E+4nM
Assay Description:
Inhibition of recombinant TCPTP (unknown origin) using pNPP as substrate by spectrophotometric analysis
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Target Info
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Target
Receptor-type tyrosine-protein phosphatase epsilon
(Homo sapiens (Human))
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50436358
(CHEMBL2396718)
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Affinity Data
IC50: >2.50E+4nM
Assay Description:
Inhibition of recombinant PTPepsilon (unknown origin) using pNPP as substrate by spectrophotometric analysis
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