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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 12 hits in this display   

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589760(US11559538, Example 124 | US11559538, Example 23 |...)
Affinity DataIC50:  0.610nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterferon gamma receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589760(US11559538, Example 124 | US11559538, Example 23 |...)
Affinity DataIC50:  0.850nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589760(US11559538, Example 124 | US11559538, Example 23 |...)
Affinity DataIC50:  0.970nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589760(US11559538, Example 124 | US11559538, Example 23 |...)
Affinity DataIC50:  2.20nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589760(US11559538, Example 124 | US11559538, Example 23 |...)
Affinity DataIC50:  2.21nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterferon gamma receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589760(US11559538, Example 124 | US11559538, Example 23 |...)
Affinity DataIC50:  2.27nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589760(US11559538, Example 124 | US11559538, Example 23 |...)
Affinity DataIC50:  3.94nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589760(US11559538, Example 124 | US11559538, Example 23 |...)
Affinity DataIC50:  9.48nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterferon gamma receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589760(US11559538, Example 124 | US11559538, Example 23 |...)
Affinity DataIC50:  10.1nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589760(US11559538, Example 124 | US11559538, Example 23 |...)
Affinity DataIC50:  132nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589760(US11559538, Example 124 | US11559538, Example 23 |...)
Affinity DataIC50:  576nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589760(US11559538, Example 124 | US11559538, Example 23 |...)
Affinity DataIC50:  1.66E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent