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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human))
Pfizer
US Patent
Ligand
BDBM589905
(US11559538, Example 156)
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Affinity Data
IC50: 0.820nM
Assay Description:
Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Interferon gamma receptor 1
(Homo sapiens (Human))
Pfizer
US Patent
Ligand
BDBM589905
(US11559538, Example 156)
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Affinity Data
IC50: 1.56nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Interleukin-4
(Human)
Pfizer
US Patent
Ligand
BDBM589905
(US11559538, Example 156)
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Affinity Data
IC50: 127nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Interleukin-13
(Human)
Pfizer
US Patent
Ligand
BDBM589905
(US11559538, Example 156)
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Copy InChI
Affinity Data
IC50: 901nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI