Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston

Curated by ChEMBL

LigandBDBM50564981(CHEMBL4786742)Copy SMILESCopy InChI

Affinity DataIC50:  32nMAssay Description:Inhibition of recombinant human RIPK2 incubated for 2 hr by ADP-Glo assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University Of Houston

Curated by ChEMBL

LigandBDBM50564981(CHEMBL4786742)Copy SMILESCopy InChI

Affinity DataIC50:  420nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetActivin receptor type-1(Homo sapiens (Human))
University Of Houston

Curated by ChEMBL

LigandBDBM50564981(CHEMBL4786742)Copy SMILESCopy InChI

Affinity DataIC50:  3.55E+3nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by kinase assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails ArticlePubMed
Copy BDB DOI