Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 16 hits in this display   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302163(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
Affinity DataIC50:  41nMAssay Description:Inhibition of Flag epitope-tagged IKK-beta preincubated for 5 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302163(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
Affinity DataIC50:  90nMAssay Description:Inhibition of IKKalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302163(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
Affinity DataIC50: >7.00E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302163(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
Affinity DataIC50: >7.00E+3nMAssay Description:Inhibition of FGFR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 3(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302163(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of HekMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302163(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
Affinity DataIC50: >7.00E+3nMAssay Description:Inhibition of HGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302163(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
Affinity DataIC50: >7.00E+3nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302163(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
Affinity DataIC50: >7.00E+3nMAssay Description:Inhibition of IRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302163(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
Affinity DataIC50: >7.00E+3nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302163(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
Affinity DataIC50: >7.00E+3nMAssay Description:Inhibition of PDGFRalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302163(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
Affinity DataIC50: >7.00E+3nMAssay Description:Inhibition of SykMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302163(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
Affinity DataIC50: >7.00E+3nMAssay Description:Inhibition of TrkAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302163(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
Affinity DataIC50: >7.00E+3nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302163(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
Affinity DataIC50: >7.00E+3nMAssay Description:Inhibition of BtkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302163(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
Affinity DataIC50: >7.00E+3nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302163(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
Affinity DataIC50: >7.00E+3nMAssay Description:Inhibition of EckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed