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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
16
hits in this display
Target
Inhibitor of nuclear factor kappa-B kinase subunit beta
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50302163
(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
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Affinity Data
IC50: 41nM
Assay Description:
Inhibition of Flag epitope-tagged IKK-beta preincubated for 5 mins by scintillation proximity assay
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Inhibitor of nuclear factor kappa-B kinase subunit alpha
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50302163
(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
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Copy InChI
Affinity Data
IC50: 90nM
Assay Description:
Inhibition of IKKalpha
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50302163
(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
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Affinity Data
IC50: >7.00E+3nM
Assay Description:
Inhibition of EGFR
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Fibroblast growth factor receptor 3
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50302163
(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
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Affinity Data
IC50: >7.00E+3nM
Assay Description:
Inhibition of FGFR3
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Ephrin type-A receptor 3
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50302163
(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
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Copy InChI
Affinity Data
IC50: 7.00E+3nM
Assay Description:
Inhibition of Hek
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Hepatocyte growth factor receptor
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50302163
(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
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Copy InChI
Affinity Data
IC50: >7.00E+3nM
Assay Description:
Inhibition of HGFR
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Insulin-like growth factor 1 receptor
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50302163
(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
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Copy InChI
Affinity Data
IC50: >7.00E+3nM
Assay Description:
Inhibition of IGF1R
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Insulin receptor
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50302163
(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
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Copy InChI
Affinity Data
IC50: >7.00E+3nM
Assay Description:
Inhibition of IR
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Lyn
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50302163
(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
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Copy InChI
Affinity Data
IC50: >7.00E+3nM
Assay Description:
Inhibition of Lyn
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50302163
(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
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Affinity Data
IC50: >7.00E+3nM
Assay Description:
Inhibition of PDGFRalpha
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
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Target
Tyrosine-protein kinase SYK
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50302163
(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >7.00E+3nM
Assay Description:
Inhibition of Syk
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50302163
(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >7.00E+3nM
Assay Description:
Inhibition of TrkA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50302163
(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >7.00E+3nM
Assay Description:
Inhibition of VEGFR1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase BTK
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50302163
(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >7.00E+3nM
Assay Description:
Inhibition of Btk
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ITK/TSK
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50302163
(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >7.00E+3nM
Assay Description:
Inhibition of Itk
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ephrin type-A receptor 2
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50302163
(3-amino-6-(4-aminopiperidin-1-yl)-4-propylthieno[2...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >7.00E+3nM
Assay Description:
Inhibition of Eck
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI