Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
University Institute Of Pathology

Curated by ChEMBL
LigandPNGBDBM50159365((3R,5S)-5-{[(2,5-difluorobenzyl)amino]methyl}-1-(5...)
Affinity DataIC50:  10.4nMAssay Description:Inhibitory concentration against human ECE-1 by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
University Institute Of Pathology

Curated by ChEMBL
LigandPNGBDBM50159365((3R,5S)-5-{[(2,5-difluorobenzyl)amino]methyl}-1-(5...)
Affinity DataIC50:  72.9nMAssay Description:Inhibitory concentration against human ECE-1 expressed in MDCK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
University Institute Of Pathology

Curated by ChEMBL
LigandPNGBDBM50159365((3R,5S)-5-{[(2,5-difluorobenzyl)amino]methyl}-1-(5...)
Affinity DataIC50:  3.15E+4nMAssay Description:Inhibitory concentration against human angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
University Institute Of Pathology

Curated by ChEMBL
LigandPNGBDBM50159365((3R,5S)-5-{[(2,5-difluorobenzyl)amino]methyl}-1-(5...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against NeprilysinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed