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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
A disintegrin and metalloproteinase with thrombospondin motifs 4
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50122449
(CHEMBL3622483)
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Affinity Data
IC50: 10nM
Assay Description:
Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Collagenase 3
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50122449
(CHEMBL3622483)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human recombinant MMP13 using 5-FAMTPGPLGL[Dap(DNP)]ARRK(5-TAMRA)-amide as substrate after 45 mins
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50122449
(CHEMBL3622483)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of ADAMTS5 (unknown origin) using WAAG-3R as substrate preincubated for 15 mins followed by substrate addition measured every 30 secs for ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
A disintegrin and metalloproteinase with thrombospondin motifs 13
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50122449
(CHEMBL3622483)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human recombinant ADAMTS13 using FRETSVWF73 as substrate by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50122449
(CHEMBL3622483)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human recombinant TACE using Mca-PLAQAV-Dpa-RSSSR-NH2 as substrate preincubated for 15 mins measured every 30 secs for 30 mins by fluor...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI