Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL

LigandBDBM50213947(3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N1,N1-...)Copy SMILESCopy InChI

Affinity DataIC50:  9.60nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL

LigandBDBM50213947(3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N1,N1-...)Copy SMILESCopy InChI

Affinity DataIC50:  1.74E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI