Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL

LigandBDBM50181009((3S,6S)-4-(4-(but-2-ynyloxy)phenylsulfonyl)-6-(2-(...)Copy SMILESCopy InChI

Affinity DataIC50:  33nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL

LigandBDBM50181009((3S,6S)-4-(4-(but-2-ynyloxy)phenylsulfonyl)-6-(2-(...)Copy SMILESCopy InChI

Affinity DataIC50:  48nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL

LigandBDBM50181009((3S,6S)-4-(4-(but-2-ynyloxy)phenylsulfonyl)-6-(2-(...)Copy SMILESCopy InChI

Affinity DataIC50:  143nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI