Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL

LigandBDBM50437640(CHEMBL1684983)Copy SMILESCopy InChI

Affinity DataIC50:  37nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL

LigandBDBM50437640(CHEMBL1684983)Copy SMILESCopy InChI

Affinity DataIC50:  510nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL

LigandBDBM50437640(CHEMBL1684983)Copy SMILESCopy InChI

Affinity DataIC50:  2.45E+4nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in presence of human serum albuminMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI