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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
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Target
Complement factor B
(Homo sapiens (Human))
The University Of Queensland
Curated by
ChEMBL
Ligand
BDBM251408
(US9452990, 90)
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Affinity Data
IC50: 1nM
Assay Description:
Inhibition of recombinant human factor B expressed in drosophila cells assessed as decrease in C3a formation using CVF-Bb complex and human complemen...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Cobra venom factor/Complement factor B/Complement factor D
(Naja kaouthia (Monocled cobra) (Naja siamensis))
Novartis
US Patent
Ligand
BDBM251408
(US9452990, 90)
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Affinity Data
IC50: 1nM
pH: 7.4 T: 2°C
Assay Description:
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI