Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Horizon Discovery

Curated by ChEMBL

LigandBDBM50437711(CHEMBL2409076)Copy SMILESCopy InChI

Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Pin1 (unknown origin) using Suc-Ala-Glu-Pro-Phe-MCA as substrate after 120 secs by fluorescence microtiter plate reader analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Horizon Discovery

Curated by ChEMBL

LigandBDBM50437711(CHEMBL2409076)Copy SMILESCopy InChI

Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human Pin1 assessed as reduction in PPIase activity using Suc-Ala-Glu-Pro-Phe-MCA as substrate measured for 20 secs by fluorescence met...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 4(Homo sapiens (Human))
Horizon Discovery

Curated by ChEMBL

LigandBDBM50437711(CHEMBL2409076)Copy SMILESCopy InChI

Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Par14 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI