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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Collagenase 3
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50361633
(CHEMBL1939875 | US8785489, ethyl 5-(1-methyl-3-{[(...)
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Affinity Data
IC50: 120nM
Assay Description:
Inhibition of human MMP13 expressed in Escherichia coli after 30 mins by fluorimetry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Collagenase 3
(Mus musculus (Mouse))
Boehringer Ingelheim International
US Patent
Ligand
BDBM50361633
(CHEMBL1939875 | US8785489, ethyl 5-(1-methyl-3-{[(...)
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Copy InChI
Affinity Data
IC50: 125nM
Assay Description:
The EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.) can detect the activity of several MMPs including MMP-1, 2, 3, 7, 8, 9, 13, and 14. This kit us...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50361633
(CHEMBL1939875 | US8785489, ethyl 5-(1-methyl-3-{[(...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 280nM
Assay Description:
Inhibition of MMP13 after 30 mins by fluorimetry in the presence of 1.25% human serum albumin
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-14
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50361633
(CHEMBL1939875 | US8785489, ethyl 5-(1-methyl-3-{[(...)
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Affinity Data
IC50: 1.10E+4nM
Assay Description:
Inhibition of human recombinant MMP14 after 60 mins by fluorimetry
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50361633
(CHEMBL1939875 | US8785489, ethyl 5-(1-methyl-3-{[(...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.40E+4nM
Assay Description:
Inhibition of human recombinant MMP2 after 30 mins by fluorimetry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI