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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetCollagenase 3(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50361633(CHEMBL1939875 | US8785489, ethyl 5-(1-methyl-3-{[(...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human MMP13 expressed in Escherichia coli after 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Mus musculus (Mouse))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50361633(CHEMBL1939875 | US8785489, ethyl 5-(1-methyl-3-{[(...)
Affinity DataIC50:  125nMAssay Description:The EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.) can detect the activity of several MMPs including MMP-1, 2, 3, 7, 8, 9, 13, and 14. This kit us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCollagenase 3(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50361633(CHEMBL1939875 | US8785489, ethyl 5-(1-methyl-3-{[(...)
Affinity DataIC50:  280nMAssay Description:Inhibition of MMP13 after 30 mins by fluorimetry in the presence of 1.25% human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50361633(CHEMBL1939875 | US8785489, ethyl 5-(1-methyl-3-{[(...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human recombinant MMP14 after 60 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50361633(CHEMBL1939875 | US8785489, ethyl 5-(1-methyl-3-{[(...)
Affinity DataIC50: >2.40E+4nMAssay Description:Inhibition of human recombinant MMP2 after 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed