Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL

LigandBDBM50361625(CHEMBL1939867)Copy SMILESCopy InChI

Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human recombinant MMP14 after 60 mins by fluorimetryMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

Target72 kDa type IV collagenase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL

LigandBDBM50361625(CHEMBL1939867)Copy SMILESCopy InChI

Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human recombinant MMP2 after 30 mins by fluorimetryMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCollagenase 3(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL

LigandBDBM50361625(CHEMBL1939867)Copy SMILESCopy InChI

Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human MMP13 expressed in Escherichia coli after 30 mins by fluorimetryMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI