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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 16 hits in this display   

TargetIsoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589749(US11559538, Example 13)
Affinity DataIC50:  0.970nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterferon gamma receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589748(US11559538, Example 12 | US11559538, Example 214 |...)
Affinity DataIC50:  0.990nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589748(US11559538, Example 12 | US11559538, Example 214 |...)
Affinity DataIC50:  1.08nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterferon gamma receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589748(US11559538, Example 12 | US11559538, Example 214 |...)
Affinity DataIC50:  1.34nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589748(US11559538, Example 12 | US11559538, Example 214 |...)
Affinity DataIC50:  2.32nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589748(US11559538, Example 12 | US11559538, Example 214 |...)
Affinity DataIC50:  2.5nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterferon gamma receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589749(US11559538, Example 13)
Affinity DataIC50:  4.89nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589748(US11559538, Example 12 | US11559538, Example 214 |...)
Affinity DataIC50:  4.92nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589749(US11559538, Example 13)
Affinity DataIC50:  5.98nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589748(US11559538, Example 12 | US11559538, Example 214 |...)
Affinity DataIC50:  7.22nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterferon gamma receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589748(US11559538, Example 12 | US11559538, Example 214 |...)
Affinity DataIC50:  13.7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589748(US11559538, Example 12 | US11559538, Example 214 |...)
Affinity DataIC50:  20.7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589748(US11559538, Example 12 | US11559538, Example 214 |...)
Affinity DataIC50:  162nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589749(US11559538, Example 13)
Affinity DataIC50:  166nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589748(US11559538, Example 12 | US11559538, Example 214 |...)
Affinity DataIC50:  167nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589748(US11559538, Example 12 | US11559538, Example 214 |...)
Affinity DataIC50:  2.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent