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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Aurora kinase B/Inner centromere protein
(Homo sapiens (Human))
Nirma University
Curated by
ChEMBL
Ligand
BDBM209861
(5-(3-ethylsulfonylphenyl)-3,8-dimethyl-N-(1-methyl...)
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Affinity Data
Ki: 0.0200nM
Assay Description:
Inhibition of Aurora B/INCENP (unknown origin) assessed as affinity constant pre-incubated for 1 hr followed by FL-PKAtide substrate and ATP addition
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Target
Ephrin type-A receptor 2 [596-900]
(Homo sapiens (Human))
Technical University of Munich
Ligand
BDBM209861
(5-(3-ethylsulfonylphenyl)-3,8-dimethyl-N-(1-methyl...)
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Affinity Data
IC50: 4.80nM
Assay Description:
Refer to Reaction Biology Corps.
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
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In Depth
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Article
PubMed
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Target
Aurora kinase B/Inner centromere protein
(Homo sapiens (Human))
Nirma University
Curated by
ChEMBL
Ligand
BDBM209861
(5-(3-ethylsulfonylphenyl)-3,8-dimethyl-N-(1-methyl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 15nM
Assay Description:
Inhibition of Aurora B/INCENP (unknown origin) pre-incubated for 1 hr followed by FL-PKAtide substrate and ATP addition
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Aurora kinase A/Targeting protein for Xklp2
(Homo sapiens (Human))
Nirma University
Curated by
ChEMBL
Ligand
BDBM209861
(5-(3-ethylsulfonylphenyl)-3,8-dimethyl-N-(1-methyl...)
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Affinity Data
IC50: 21nM
Assay Description:
Inhibition of Aurora A/TPX2 (unknown origin) pre-incubated for 1 hr followed by FL-Kemptide substrate and ATP addition
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
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MCE
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PC sid
In Depth
Details
Article
PubMed
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Target
Ephrin type-A receptor 2 [596-900]
(Homo sapiens (Human))
Technical University of Munich
Ligand
BDBM209861
(5-(3-ethylsulfonylphenyl)-3,8-dimethyl-N-(1-methyl...)
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Affinity Data
Kd: 198nM
Assay Description:
Kinobeads competition assays were performed in 96-well format as previously described using mixed protein lysates of four cancer cell lines (K-562, M...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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MCE
PC cid
PC sid
In Depth
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Article
PubMed
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