Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Phospholipase A2, membrane associated
(Homo sapiens (Human))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM23771
((3-{[1-benzyl-3-(carbamoylmethyl)-2-ethyl-1H-indol...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 23nM
Assay Description:
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Phospholipase A2, membrane associated
(Homo sapiens (Human))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM23771
((3-{[1-benzyl-3-(carbamoylmethyl)-2-ethyl-1H-indol...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 470nM
Assay Description:
Inhibition of human recombinant group 2A phospholipase A2 by fluorimetric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Phospholipase A2, membrane associated
(Homo sapiens (Human))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM23771
((3-{[1-benzyl-3-(carbamoylmethyl)-2-ethyl-1H-indol...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 470nM
Assay Description:
Inhibition of human group IIA PLA2 by fluorimetric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Phospholipase A2, membrane associated
(Homo sapiens (Human))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM23771
((3-{[1-benzyl-3-(carbamoylmethyl)-2-ethyl-1H-indol...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 470nM
pH: 7.5 T: 2°C
Assay Description:
PLA2 activity is by using the fluorescent phospholipid analogue, beta-pyC-10-PG as the substrate. The increase in fluorescence (ex @342 nm and em@388...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Phospholipase A2, major isoenzyme
(Sus scrofa (pig))
Universite Paris 7-Denis Diderot
Ligand
BDBM23771
((3-{[1-benzyl-3-(carbamoylmethyl)-2-ethyl-1H-indol...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.00E+3nM
Assay Description:
PLA2 activity is by using the fluorescent phospholipid analogue as the substrate. The increase in fluorescence (ex @342 nm and em@388 nm) of the enzy...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phospholipase A2, major isoenzyme
(Sus scrofa (pig))
Universite Paris 7-Denis Diderot
Ligand
BDBM23771
((3-{[1-benzyl-3-(carbamoylmethyl)-2-ethyl-1H-indol...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.00E+3nM
Assay Description:
Inhibition of pig group IB PLA2 by fluorimetric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phospholipase A2, major isoenzyme
(Sus scrofa (pig))
Universite Paris 7-Denis Diderot
Ligand
BDBM23771
((3-{[1-benzyl-3-(carbamoylmethyl)-2-ethyl-1H-indol...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.00E+3nM
Assay Description:
Inhibition of porcine group 1B phospholipase A2 by fluorimetric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phospholipase A2, membrane associated
(Homo sapiens (Human))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM23771
((3-{[1-benzyl-3-(carbamoylmethyl)-2-ethyl-1H-indol...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.55E+4nM
Assay Description:
Inhibitory activity against porcine pancreatic Phospholipase A2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Phospholipase A2, membrane associated
(Homo sapiens (Human))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM23771
((3-{[1-benzyl-3-(carbamoylmethyl)-2-ethyl-1H-indol...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.11E+4nM
Assay Description:
Inhibitory activity against human pancreatic Phospholipase A2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI