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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Fructose-1,6-bisphosphatase 1
(Homo sapiens (Human))
Metabasis Therapeutics
Curated by
ChEMBL
Ligand
BDBM50303854
(5-(4-amino-7-ethyl-5-fluoro-1-isobutyl-1H-benzo[d]...)
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Affinity Data
IC50: 55nM
Assay Description:
Inhibition of human liver FBPase 1
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Fructose-1,6-bisphosphatase 1
(Homo sapiens (Human))
Metabasis Therapeutics
Curated by
ChEMBL
Ligand
BDBM50303854
(5-(4-amino-7-ethyl-5-fluoro-1-isobutyl-1H-benzo[d]...)
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Copy InChI
Affinity Data
IC50: 90nM
Assay Description:
Inhibition of human liver FBPase expressed in Escherichia coli
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Fructose-1,6-bisphosphatase 1
(Homo sapiens (Human))
Metabasis Therapeutics
Curated by
ChEMBL
Ligand
BDBM50303854
(5-(4-amino-7-ethyl-5-fluoro-1-isobutyl-1H-benzo[d]...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 90nM
Assay Description:
Inhibition of human liver FBP
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Fructose-1,6-bisphosphatase 1
(Rattus norvegicus)
Metabasis Therapeutics
Curated by
ChEMBL
Ligand
BDBM50303854
(5-(4-amino-7-ethyl-5-fluoro-1-isobutyl-1H-benzo[d]...)
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Copy InChI
Affinity Data
IC50: 550nM
Assay Description:
Inhibition of rat liver FBPase 1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Fructose-1,6-bisphosphatase 1
(Homo sapiens (Human))
Metabasis Therapeutics
Curated by
ChEMBL
Ligand
BDBM50303854
(5-(4-amino-7-ethyl-5-fluoro-1-isobutyl-1H-benzo[d]...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.00E+4nM
Assay Description:
Inhibition of human liver FBPase expressed in Escherichia coli by spectrophotometry method
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Adenosine kinase
(Homo sapiens (Human))
Metabasis Therapeutics
Curated by
ChEMBL
Ligand
BDBM50303854
(5-(4-amino-7-ethyl-5-fluoro-1-isobutyl-1H-benzo[d]...)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of adenosine kinase AMP binding site
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Adenosine deaminase
(Homo sapiens (Human))
Metabasis Therapeutics
Curated by
ChEMBL
Ligand
BDBM50303854
(5-(4-amino-7-ethyl-5-fluoro-1-isobutyl-1H-benzo[d]...)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of AMP deaminase AMP binding site
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-dependent 6-phosphofructokinase, muscle type
(Homo sapiens (Human))
Metabasis Therapeutics
Curated by
ChEMBL
Ligand
BDBM50303854
(5-(4-amino-7-ethyl-5-fluoro-1-isobutyl-1H-benzo[d]...)
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Copy InChI
Affinity Data
EC50: >1.00E+5nM
Assay Description:
Inhibition of phosphofructokinase AMP binding site
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI