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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetInterleukin-17A(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM419248(N-(4-ethylphenyl)-4-((S)-3- hydroxypyrrolidin-1-yl...)
Affinity DataIC50: >1.00E+3nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM419248(N-(4-ethylphenyl)-4-((S)-3- hydroxypyrrolidin-1-yl...)
Affinity DataIC50: >1.00E+3nMAssay Description:The RORγ transactivation model was developed from the line HG5LN, which is a HeLa line that stably expresses a luciferase reporter gene controll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent