Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetInterleukin-17A(Homo sapiens (Human))
Galderma Research & Development

US Patent

LigandBDBM419242(N-(4-ethylphenyl)-N- isobutyl-3-(S- methylsulfonim...)Copy SMILESCopy InChI

Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Galderma Research & Development

US Patent

LigandBDBM419242(N-(4-ethylphenyl)-N- isobutyl-3-(S- methylsulfonim...)Copy SMILESCopy InChI

Affinity DataIC50: <100nMAssay Description:The RORγ transactivation model was developed from the line HG5LN, which is a HeLa line that stably expresses a luciferase reporter gene controll...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI