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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Interleukin-17A
(Homo sapiens (Human))
Galderma Research & Development
US Patent
Ligand
BDBM50461068
(CHEMBL4228069 | US10457637, Compound 24)
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Affinity Data
IC50: <100nM
Assay Description:
This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Nuclear receptor ROR-gamma
(Homo sapiens (Human))
Nestle Skin Health
Curated by
ChEMBL
Ligand
BDBM50461068
(CHEMBL4228069 | US10457637, Compound 24)
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Affinity Data
IC50: 210nM
Assay Description:
Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Nuclear receptor ROR-gamma
(Homo sapiens (Human))
Nestle Skin Health
Curated by
ChEMBL
Ligand
BDBM50461068
(CHEMBL4228069 | US10457637, Compound 24)
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Copy InChI
Affinity Data
IC50: 550nM
Assay Description:
The RORγ transactivation model was developed from the line HG5LN, which is a HeLa line that stably expresses a luciferase reporter gene controll...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI