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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Nuclear receptor ROR-gamma
(Homo sapiens (Human))
Galderma Research & Development
US Patent
Ligand
BDBM419147
(N-(4-ethylphenyl)-N- isobutyl-4-(tetrahydropyran- ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 550nM
Assay Description:
The RORγ transactivation model was developed from the line HG5LN, which is a HeLa line that stably expresses a luciferase reporter gene controll...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Interleukin-17A
(Homo sapiens (Human))
Galderma Research & Development
US Patent
Ligand
BDBM419147
(N-(4-ethylphenyl)-N- isobutyl-4-(tetrahydropyran- ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 550nM
Assay Description:
This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Interleukin-17A
(Homo sapiens (Human))
Galderma Research & Development
US Patent
Ligand
BDBM419148
(N-(4-ethylphenyl)-N- isobutyl-4-(tetrahydropyran- ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 550nM
Assay Description:
This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Interleukin-17A
(Homo sapiens (Human))
Galderma Research & Development
US Patent
Ligand
BDBM419148
(N-(4-ethylphenyl)-N- isobutyl-4-(tetrahydropyran- ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 550nM
Assay Description:
This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Nuclear receptor ROR-gamma
(Homo sapiens (Human))
Galderma Research & Development
US Patent
Ligand
BDBM419148
(N-(4-ethylphenyl)-N- isobutyl-4-(tetrahydropyran- ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 550nM
Assay Description:
The RORγ transactivation model was developed from the line HG5LN, which is a HeLa line that stably expresses a luciferase reporter gene controll...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Nuclear receptor ROR-gamma
(Homo sapiens (Human))
Galderma Research & Development
US Patent
Ligand
BDBM419148
(N-(4-ethylphenyl)-N- isobutyl-4-(tetrahydropyran- ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 550nM
Assay Description:
The RORγ transactivation model was developed from the line HG5LN, which is a HeLa line that stably expresses a luciferase reporter gene controll...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI