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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 9 hits in this display   

TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50173228((S)-2-{4'-[(5-Ethyl-4-methoxy-3-methyl-benzofuran-...)
Affinity DataIC50:  3.80nMAssay Description:Inhibitory concentration against MMP-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50173228((S)-2-{4'-[(5-Ethyl-4-methoxy-3-methyl-benzofuran-...)
Affinity DataIC50:  101nMAssay Description:Inhibitory concentration against MMP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50173228((S)-2-{4'-[(5-Ethyl-4-methoxy-3-methyl-benzofuran-...)
Affinity DataIC50:  561nMAssay Description:Inhibitory concentration against MMP-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50173228((S)-2-{4'-[(5-Ethyl-4-methoxy-3-methyl-benzofuran-...)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibitory concentration against MMP-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50173228((S)-2-{4'-[(5-Ethyl-4-methoxy-3-methyl-benzofuran-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibitory concentration against MMP-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50173228((S)-2-{4'-[(5-Ethyl-4-methoxy-3-methyl-benzofuran-...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibitory concentration against Aggrecanase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50173228((S)-2-{4'-[(5-Ethyl-4-methoxy-3-methyl-benzofuran-...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibitory concentration against MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50173228((S)-2-{4'-[(5-Ethyl-4-methoxy-3-methyl-benzofuran-...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory concentration against MMP-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50173228((S)-2-{4'-[(5-Ethyl-4-methoxy-3-methyl-benzofuran-...)
Affinity DataIC50:  3.02E+4nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed