Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 12 hits in this display   

TargetGTPase KRas [Q61H](Homo sapiens (Human))
Revolution Medicines

US Patent
LigandPNGBDBM591865(US11566007, Example A545)
Affinity DataIC50:  55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGTPase KRas [G12C](Homo sapiens (Human))
Revolution Medicines

US Patent
LigandPNGBDBM591865(US11566007, Example A545)
Affinity DataIC50:  55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGTPase KRas [G13C](Homo sapiens (Human))
Revolution Medicines

US Patent
LigandPNGBDBM591865(US11566007, Example A545)
Affinity DataIC50:  55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGTPase NRas [G12C](Homo sapiens (Human))
Revolution Medicines

US Patent
LigandPNGBDBM591865(US11566007, Example A545)
Affinity DataIC50:  55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGTPase NRas [Q61K](Homo sapiens (Human))
Revolution Medicines

US Patent
LigandPNGBDBM591865(US11566007, Example A545)
Affinity DataIC50:  55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGTPase NRas [Q61R](Homo sapiens (Human))
Revolution Medicines

US Patent
LigandPNGBDBM591865(US11566007, Example A545)
Affinity DataIC50:  550nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGTPase KRas(Homo sapiens (Human))
Revolution Medicines

US Patent
LigandPNGBDBM591865(US11566007, Example A545)
Affinity DataIC50:  550nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGTPase KRas [G12S](Homo sapiens (Human))
Revolution Medicines

US Patent
LigandPNGBDBM591865(US11566007, Example A545)
Affinity DataIC50:  550nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGTPase KRas [G13D](Homo sapiens (Human))
Revolution Medicines

US Patent
LigandPNGBDBM591865(US11566007, Example A545)
Affinity DataIC50:  550nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGTPase NRas(Homo sapiens (Human))
Revolution Medicines

US Patent
LigandPNGBDBM591865(US11566007, Example A545)
Affinity DataIC50:  550nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGTPase KRas [G12V](Homo sapiens (Human))
Revolution Medicines

US Patent
LigandPNGBDBM591865(US11566007, Example A545)
Affinity DataIC50:  550nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Revolution Medicines

US Patent
LigandPNGBDBM591865(US11566007, Example A545)
Affinity DataIC50:  5.50E+3nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent