Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 16 hits in this display
BDBM454213((Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-d...)
BDBM454213((Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-d...)
IC50: <300nMAssay Description:LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...More data for this Ligand-Target Pair
BDBM454213((Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-d...)
IC50: >300nMAssay Description:LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...More data for this Ligand-Target Pair
BDBM454213((Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-d...)
BDBM454213((Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-d...)
IC50: >300nMAssay Description:LOX: The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the i...More data for this Ligand-Target Pair
BDBM454213((Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-d...)
IC50: <300nMAssay Description:LOX: The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the i...More data for this Ligand-Target Pair
BDBM454213((Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-d...)
IC50: >300nMAssay Description:LOX: The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the i...More data for this Ligand-Target Pair
BDBM454213((Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-d...)
IC50: <300nMAssay Description:LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...More data for this Ligand-Target Pair
BDBM454213((Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-d...)
BDBM454213((Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-d...)
BDBM454213((Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-d...)
IC50: >3.00E+3nMAssay Description:Human recombinant SSAO/VAP-1 amine oxidase activity was determined using the coupled colorimetric method as described for monoamine oxidase, copper-c...More data for this Ligand-Target Pair
BDBM454213((Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-d...)
IC50: >3.00E+3nMAssay Description:Mao-B: The specificity of the compounds of this invention was tested by determining their ability to inhibit MAO-B activities in vitro. Recombinant h...More data for this Ligand-Target Pair
BDBM454213((Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-d...)
BDBM454213((Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-d...)
BDBM454213((Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-d...)
IC50: >3.00E+3nMAssay Description:Human recombinant SSAO/VAP-1 amine oxidase activity was determined using the coupled colorimetric method as described for monoamine oxidase, copper-c...More data for this Ligand-Target Pair
BDBM454213((Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-d...)
IC50: >3.00E+3nMAssay Description:MAO-B: The specificity of the compounds of this invention was tested by determining their ability to inhibit MAO-B activities in vitro. Recombinant h...More data for this Ligand-Target Pair