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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
CREB-binding protein
(Homo sapiens (Human))
Genentech
US Patent
Ligand
BDBM50200457
(CHEMBL3943463 | US9763922, Example 220)
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Affinity Data
IC50: 290nM
Assay Description:
His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
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Target
CREB-binding protein/Histone acetyltransferase p300
(Homo sapiens (Human))
Genentech
Curated by
ChEMBL
Ligand
BDBM50200457
(CHEMBL3943463 | US9763922, Example 220)
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Affinity Data
IC50: 360nM
Assay Description:
Displacement of biotinylated ligand from recombinant His-tagged CBP/EP300 (unknown origin) measured after 10 mins by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
Genentech
US Patent
Ligand
BDBM50200457
(CHEMBL3943463 | US9763922, Example 220)
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Affinity Data
IC50: 9.72E+3nM
Assay Description:
His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
Genentech
US Patent
Ligand
BDBM50200457
(CHEMBL3943463 | US9763922, Example 220)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.30E+4nM
Assay Description:
Displacement of biotinylated ligand from recombinant His-tagged BRD4 bromodomain-1 (unknown origin) measured after 10 mins by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI