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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
Lysine-specific demethylase 5B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513348
(CHEMBL4585876)
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Affinity Data
Ki: 4nM
Assay Description:
Binding affinity to KDM5B (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 4A
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513348
(CHEMBL4585876)
Copy SMILES
Copy InChI
Affinity Data
Ki: 4nM
Assay Description:
Binding affinity to KDM4A (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Lysine-specific demethylase 5B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513348
(CHEMBL4585876)
Copy SMILES
Copy InChI
Affinity Data
IC50: 12nM
Assay Description:
Inhibition of KDM5B (unknown origin) assessed as decrease in demethylation of substrate using peptide (H3(1-21)K4-Me3-GGKBiotin) as substrate and 2OG...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 4B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513348
(CHEMBL4585876)
Copy SMILES
Copy InChI
Affinity Data
IC50: 20nM
Assay Description:
Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrea...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 5C
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513348
(CHEMBL4585876)
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Copy InChI
Affinity Data
IC50: 48nM
Assay Description:
Inhibition of KDM5C (unknown origin) assessed as decrease in demethylation of substrate using peptide (H3(1-21)K4-Me3-GGKBiotin) as substrate and 2OG...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 4A
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513348
(CHEMBL4585876)
Copy SMILES
Copy InChI
Affinity Data
IC50: 93nM
Assay Description:
Inhibition of N-terminal His-tagged recombinant human KDM4A (1 to 359 residues) expressed in Escherichia coli assessed as decrease in demethylation o...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Lysine-specific demethylase 2A
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513348
(CHEMBL4585876)
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Affinity Data
IC50: 1.42E+3nM
Assay Description:
Inhibition of KDM2A (unknown origin) by Alphascreen assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
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Ligand Info
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Lysine-specific demethylase 3A
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513348
(CHEMBL4585876)
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Affinity Data
IC50: 2.02E+3nM
Assay Description:
Inhibition of KDM3A (unknown origin) by Alphascreen assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 6B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513348
(CHEMBL4585876)
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Affinity Data
IC50: 5.24E+4nM
Assay Description:
Inhibition of KDM6B (unknown origin) by Alphascreen assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 5B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513348
(CHEMBL4585876)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.90E+3nM
Assay Description:
Binding affinity to recombinant human N-terminal KDM5B (26 to 772 residues) fused with ePL-tagged C-terminal transfected in HEK293T cells measured af...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 4B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50513348
(CHEMBL4585876)
Copy SMILES
Copy InChI
Affinity Data
EC50: 3.50E+3nM
Assay Description:
Binding affinity to recombinant human N-terminal KDM4B (1 to 348 residues) fused upstream with E31G-R71G-K105E/ePL-tagged C-terminal transfected in H...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI