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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Oxidized low-density lipoprotein receptor 1
(Bovine)
Pharmaxis
US Patent
Ligand
BDBM454289
((Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-chloro...)
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Affinity Data
IC50: >300nM
Assay Description:
LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Lysyl oxidase homolog 2
(Homo sapiens (Human))
Pharmaxis
US Patent
Ligand
BDBM454289
((Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-chloro...)
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Copy InChI
Affinity Data
IC50: <300nM
Assay Description:
LOX: The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the i...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Oxidized low-density lipoprotein receptor 1
(Bovine)
Pharmaxis
US Patent
Ligand
BDBM454289
((Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-chloro...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >300nM
Assay Description:
LOX: The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the i...
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Lysyl oxidase homolog 2
(Homo sapiens (Human))
Pharmaxis
US Patent
Ligand
BDBM454289
((Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-chloro...)
Copy SMILES
Copy InChI
Affinity Data
IC50: <300nM
Assay Description:
LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Membrane primary amine oxidase
(Homo sapiens (Human))
Pharmaxis
US Patent
Ligand
BDBM454289
((Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-chloro...)
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Copy InChI
Affinity Data
IC50: >3.00E+3nM
Assay Description:
Human recombinant SSAO/VAP-1 amine oxidase activity was determined using the coupled colorimetric method as described for monoamine oxidase, copper-c...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Amine oxidase [flavin-containing] B
(Homo sapiens (Human))
Pharmaxis
US Patent
Ligand
BDBM454289
((Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-chloro...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+3nM
Assay Description:
Mao-B: The specificity of the compounds of this invention was tested by determining their ability to inhibit MAO-B activities in vitro. Recombinant h...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Membrane primary amine oxidase
(Homo sapiens (Human))
Pharmaxis
US Patent
Ligand
BDBM454289
((Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-chloro...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+3nM
Assay Description:
Human recombinant SSAO/VAP-1 amine oxidase activity was determined using the coupled colorimetric method as described for monoamine oxidase, copper-c...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Amine oxidase [flavin-containing] B
(Homo sapiens (Human))
Pharmaxis
US Patent
Ligand
BDBM454289
((Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-chloro...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+3nM
Assay Description:
MAO-B: The specificity of the compounds of this invention was tested by determining their ability to inhibit MAO-B activities in vitro. Recombinant h...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI