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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
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Target
Membrane primary amine oxidase
(Homo sapiens (Human))
Pharmaxis
US Patent
Ligand
BDBM454335
(US10717734, Compound 11)
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Affinity Data
IC50: >3.00E+3nM
Assay Description:
SSAO/VAP-1: Human recombinant SSAO/VAP-1 amine oxidase activity was determined using the coupled colorimetric method as described for monoamine oxida...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Amine oxidase [flavin-containing] B
(Homo sapiens (Human))
Pharmaxis
US Patent
Ligand
BDBM454335
(US10717734, Compound 11)
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Affinity Data
IC50: >3.00E+3nM
Assay Description:
MAO-B: The specificity of the compounds of this invention was tested by determining their ability to inhibit MAO-B activities in vitro. Recombinant h...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Oxidized low-density lipoprotein receptor 1
(Bovine)
Pharmaxis
US Patent
Ligand
BDBM454335
(US10717734, Compound 11)
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Affinity Data
IC50: >3.00E+5nM
Assay Description:
LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Lysyl oxidase homolog 2
(Homo sapiens (Human))
Pharmaxis
US Patent
Ligand
BDBM454335
(US10717734, Compound 11)
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Affinity Data
IC50: <3.00E+5nM
Assay Description:
LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI